Table 5. Inhibition effect on the tyrosinase of extracts from each part of Akebia quinata

Samples1) Tyrosinase inhibition (%) IC50 values (μg/mL)
62.5 μg/mL 125 μg/mL 250 μg/mL 500 μg/mL 1,000 μg/mL
AFW 32.41±0.153)g4) 35.84±0.33g 42.58±0.17g 47.15±0.13g 52.04±0.25g 694.82±3.66a
ALW 37.77±0.16d 40.23±0.12d 48.71±0.27d 55.44±0.15c 62.54±0.22c 350.38±0.57d
ASW 36.28±0.17e 38.69±0.19f 45.44±0.31e 51.79±0.25e 57.91±0.28e 374.27±2.01c
AFE 34.32±0.24f 39.72±0.20e 44.47±0.25f 50.38±0.24f 54.65±0.18f 382.42±2.53b
ALE 40.25±0.11b 43.95±0.26b 51.61±0.18b 56.59±0.17b 64.33±0.13b 196.16±0.98f
ASE 38.97±0.26c 41.48±0.28c 49.26±0.08c 53.70±0.15d 60.57±0.16d 305.60±0.69e
Ascorbic acid2) 44.43±0.20a 53.24±0.34a 62.59±0.19a 73.52±0.23a 80.37±0.21a 105.65±3.92g
AFW, extracts from Akebia quinata fruit by hot-water; ALW, extracts from Akebia quinata leaf by hot-water; ASW, extracts from Akebia quinata stem by hot-water; AFE, extracts from Akebia quinata fruit by 70% ethanol; ALE, extracts from Akebia quinata leaf by 70% ethanol; ASE, extracts from Akebia quinata stem by 70% ethanol.
Ascorbic acid was used as a positive control substance.
All values are mean±SD (n=5).
Means with different superscript letters (a-g) in the same column are significantly different at p<0.05 by Duncan’s multiple range test (a>b>c>d>e>f>g).