Table 1. Changes in body weight during in vivo study

Groups	Week 0	Week 1	Week 2	Week 3	Week 4	Week 5	Week 6	Week 7	Week 8	Week 9	Week 10	Week 11	Week 12	Week 13
Control (G1)¹⁾	19.81±0.37³⁾	20.50±0.33	21.93±0.52	22.50±0.62	23.84±0.49	23.83±0.49^2)***	25.6±0.72^***	26.50±0.67^***	27.44±0.65^***	28.22±0.67^***	29.31±1.01^***	30.82±1.14^***	32.15±1.17^***	33.48±1.15^***
HFD (G2)	19.82±0.24	20.53±0.35	23.72±0.35^***	25.79±0.27^***	27.75±0.31^***	27.95±0.84	30.5±0.60	32.82±0.74	34.67±0.85	36.09±0.93	37.52±1.14	39.48±1.23	40.43±1.11	41.36±1.08
Orlistat (10 mg/kg, G3)	19.81±0.33	20.94±0.40	24.23±0.50^***	25.96±0.58^***	27.65±0.73^***	27.92±0.58	29.8±0.35	31.5±0.68^**	31.2±0.76^***	30.82±1.14^***	29.13±1.05^***	28.43±1.08^***	28.02±1.15^***	27.45±1.15^***
Policosanol (5 mg/kg, G4)	19.82±0.27	20.85±0.40	23.85±0.22^***	25.93±0.37^***	27.97±0.45^***	27.91±0.48	30.1±0.80	32.0±0.49	33.7±0.71	35.14±0.46	36.37±1.08	38.32±0.69	37.61±0.75^***	36.81±0.83^***
Policosanol (10 mg/kg, G5)	19.92±0.31	21.02±0.37^*	24.18±0.54^***	26.04±0.46^***	28.23±0.60^***	27.95±0.48	30.7±0.42	32.1±0.46	33.6±0.48	35.05±0.53	36.82±0.73	37.51±0.79^**	36.65±0.80^***	35.52±0.73^***
Policosanol (20 mg/kg, G6)	19.92±0.27	21.05±0.43^*	24.21±0.24^***	26.32±0.50^***	28.30±0.3^***	27.98±0.49	30.4±0.60	32.2±0.97	33.6±1.32	35.13±0.50	35.14±0.80^***	34.32±0.40^***	33.03±0.39^***	31.92±0.43^***

Group 1 (G1), normal control group; Group 2 (G2), HFD-induced group; Group 3 (G3), treated orlistat drug (10 mg/kg) in HFD-induced group; Group 4 (G4), treated policosanol (5 mg/kg) in HFD-induced group; Group 5 (G5), treated policosanol (10 mg/kg) in HFD-induced group; Group 6 (G6), treated policosanol (20 mg/kg) in HFD-induced group.
Gray color means treatment of policosanol and orlistat period time in mice model.
All values are mean±SD (n=8).
p<0.05,
p<0.01, and
p<0.001 vs. Pathological control (HFD, G2).