Table 5. Inhibitory activity of digestive enzymes (pancreatic lipase, α-amylase, and α-glucosidase) in Sorghum bicolor flour blended with hydrocolloids
Parameter | Pancreatic lipase IC50 (μg/mL) | Αlpha-amylase IC50 (μg/mL) | Αlpha-glucosidase IC50 (μg/mL) |
SB1) | 66.11±0.412)d3) | 122.83±0.35d | 90.35±0.64d |
98% SB+2% BE | 67.08±0.42cd | 124.88±037cd | 93.84±0.28cd |
96% SB+4% BE | 69.43±0.30bc | 126.32±0.18bc | 95.94±0.15bc |
98% SB+2% DM | 69.01±0.60c | 126.45±0.76bc | 95.84±0.57bc |
96% SF+4% DM | 71.15±0.32bc | 127.53±0.76bc | 97.29±0.30bc |
98% SB+2% SCMC | 69.96±0.45bc | 129.87±0.59bc | 96.56±0.15bc |
96% SB+4% SCMC | 73.21±0.67b | 135.28±0.86b | 99.89±0.62b |
Orlistat | 0.48±0.02a | - | - |
Acarbose | - | 10.93±0.84a | 19.37±0.96a |
SB, wholemeal Sorghum bicolor flour; BE, Brachytegia eurycoma flour; DM, Detarium microcarpum flour; SCMC, sodium carboxymethyl cellulose.
All values are mean±SD (n=3).
Values with different lowercase superscript letters in the same column differ significantly (p<0.05).