Table 4. Inhibitory effects of 70% methanolic extract of D. takeshimana from Ulleung Island and its organic solvent-soluble portions against α-glucosidase

Samples Inhibition (%) IC50(μg/mL)
500 μg/mL 250 μg/mL 125 μg/mL 62.5 μg/mL 31.3 μg/mL
70% MeOH ext. 47.4±0.91)d2) 38.8±0.9d 29.3±0.5d 19.2±0.4d 7.3±0.4d >500a
n-Hexane layer 99.9±1.6a 90.8±1.5a 80.9±1.3a 63.8±1.0a 47.7±0.7a 55.5±0.4d
EtOAc layer 64.9±0.9c 53.4±0.9c 43.4±0.8b 29.1±0.7b 12.1±0.5c 229.3±2.3b
n-BuOH layer 24.0±0.6e 19.0±0.5e 11.3±0.3e 5.8±0.2e 2.7±0.2e >500a
H2O layer 5.2±0.5f 2.9±0.3f 1.5±0.2f 0.5±0.1f 0.1±0.03f >500a
Acarbose3) 69.1±1.1b 56.7±1.1b 41.2±0.8c 29.3±0.7c 15.8±0.5b 193.1±2.1c
1)Inhibitory effects are expressed as the mean±SD of triplicate experiments.
2)Different letters (a-f) within the same column indicate significant differences (p<0.05).
3)Acarbose was used as a positive control.