Table 4 Inhibitory effects of the 80% methanolic extract of Mongolian I. bungei and its n-hexane-, EtOAc-, n-BuOH-, and H2O-soluble portions against α-glucosidases

Samples Inhibition (%) IC50 (μg/mL)
50 25 12.5 6.3 3.1
80% MeOH ext. 90.9±1.7d1) 55.8±1.4d 22.0±1.1d 11.0±1.2d 4.9±0.3d 21.7±1.3
n-Hexane layer 97.0±1.0b 82.8±2.4c 38.9±2.1c 13.6±2.1c 6.9±0.5c 14.3±0.6
EtOAc layer 99.4±2.1a 96.6±1.4a 85.3±4.2a 64.5±1.5a 32.0±1.2a 4.6±0.1
n-BuOH layer 11.4±1.5f 9.4±0.9e 8.5±1.4e 6.7±0.5e 3.5±1.5e >200
H2O layer 92.4±2.5c 85.9±1.2b 74.8±2.0b 44.4±0.6b 27.0±2.1b 6.7±0.4
Acarbose2) 14.1±0.9e 9.3±1.9e 2.6±0.5f 2.1±0.4f 1.1±0.4f 473.2±5.5
Scavenging activities are expressed as the mean±SD of triplicate experiments. Mean separation within columns of respective seasons by Duncan’s multiple range test at p=0.05.
Acarbose was used as a positive control.