Table 1. Central composite design for response surface analysis

Exp. No.1) Extraction conditions
Ethanol concentration (%) Extraction time (h)
1 60 (1) 4 (1)
2 60 (1) 2 (-1)
3 20 (-1) 4 (1)
4 20 (1) 2 (-1)
5 40 (0) 3 (0)
6 40 (0) 3 (0)
7 80 (2) 3 (0)
8 0 (-2) 3 (0)
9 40 (0) 5 (2)
10 40 (0) 1 (-2)
1)The number of experimental conditions by central composite design.