Table 3.
Inhibitory effects of the methanolic extract of A. asphodeloides and its n-hexane, EtOAc-, n-BuOH-, and H2O-soluble portions against pancreatic lipase

Conc. (mg/mL) Inhibition (%)1) IC50 (mg/ml)
1000 500 250 125 62.5 31.3
70% MeOH ext. 74.3 82.6 54.6 44.2 46.7 -3) 167.2±46.7
n-Hexane layer - - - - - - >1000
EtOAc layer 87.4 83.1 80.1 77.1 72.4 50.4 31.3±0.1
n-BuOH layer 72.4 32.3 25.6 13.8 1.7 19.6 673.7±96.5
H2O layer 86.7 86.7 76.7 50.4 46.2 45,7 90.1±14.7
Orlistat2) 100 100 100 92.2 92.7 91.8 0.2±0.1
Data represent the mean±SD three replications.
Orlistat was used as a positive control.
Not detected